The "Normal" Cholesterol Myth: Detecting the Widowmaker Before It Strikes

The "Normal" Cholesterol Myth: Detecting the Widowmaker Before It Strikes

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December 20, 2025

Heart disease is still the #1 killer worldwide, yet 50-75% of people who suffer a heart attack have "normal" cholesterol levels.

Traditional cardiology waits for symptoms—chest pain, shortness of breath, or cardiac arrest—before treating the problem. Dr. John Osborne, MD, PhD, argues this is like waiting for Stage 4 cancer before ordering a screening.

In this episode, we dismantle "20th Century Cardiology." We explain why standard EKGs and stress tests fail to detect early plaque and why the "Cardiac Colonoscopy"—AI-enabled CCTA—is the only way to truly visualize your risk. We also dive deep into advanced reversal protocols, including the use of Colchicine for inflammation, the "Keto Paradox," and the genetic biomarkers (Lp(a) and ApoB) that you need to request immediately.

Topics Covered:

• The Failure of "Gold Standards": Why stress tests miss 30-40% of dangerous blockages.

• Soft Plaque vs. Hard Plaque: Understanding the difference between stable calcium and the "lava" that causes sudden death.

• Advanced Imaging: How AI CCTA visualizes the vessel wall (the "donut") rather than just the hole.

• Protocols for Reversal: The role of Colchicine, PCSK9 inhibitors, and statins in shrinking plaque.

• The Keto Paradox: Can you have healthy arteries with high cholesterol?

• Genetics: Why everyone needs to test for Lipoprotein(a) once in their life.

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